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Quantitative and Probabilistic Modeling in Pathway Logic
A. Abate, Y. Bai, N. Sznajder, C. Talcott, A. Tiwari

Citation
A. Abate, Y. Bai, N. Sznajder, C. Talcott, A. Tiwari. "Quantitative and Probabilistic Modeling in Pathway Logic". Proceedings of the 7th IEEE International Conference on BioInformatics and BioEngineering, 922-929, October, 2007.

Abstract
This paper presents a study of possible extensions of pathway logic to represent and reason about semiquantitative and probabilistic aspects of biological processes. The underlying theme is the annotation of reaction rules with affinity information that can be used in different simulation strategies. Several such strategies were implemented, and experiments carried out to test feasibility, and to compare results of different approaches. Dimerization in the ErbB signalling network, important in cancer biology, was used as a test case.

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  • HTML
    A. Abate, Y. Bai, N. Sznajder, C. Talcott, A. Tiwari. <a
    href="http://chess.eecs.berkeley.edu/pubs/442.html"
    >Quantitative and Probabilistic Modeling in Pathway
    Logic</a>, Proceedings of the 7th IEEE International
    Conference on BioInformatics and BioEngineering, 922-929,
    October, 2007.
  • Plain text
    A. Abate, Y. Bai, N. Sznajder, C. Talcott, A. Tiwari.
    "Quantitative and Probabilistic Modeling in Pathway
    Logic". Proceedings of the 7th IEEE International
    Conference on BioInformatics and BioEngineering, 922-929,
    October, 2007.
  • BibTeX
    @inproceedings{AbateBaiSznajderTalcottTiwari07_QuantitativeProbabilisticModelingInPathwayLogic,
        author = {A. Abate and Y. Bai and N. Sznajder and C. Talcott
                  and A. Tiwari},
        title = {Quantitative and Probabilistic Modeling in Pathway
                  Logic},
        booktitle = {Proceedings of the 7th IEEE International
                  Conference on BioInformatics and BioEngineering},
        pages = {922-929},
        month = {October},
        year = {2007},
        abstract = {This paper presents a study of possible extensions
                  of pathway logic to represent and reason about
                  semiquantitative and probabilistic aspects of
                  biological processes. The underlying theme is the
                  annotation of reaction rules with affinity
                  information that can be used in different
                  simulation strategies. Several such strategies
                  were implemented, and experiments carried out to
                  test feasibility, and to compare results of
                  different approaches. Dimerization in the ErbB
                  signalling network, important in cancer biology,
                  was used as a test case.},
        URL = {http://chess.eecs.berkeley.edu/pubs/442.html}
    }
    

Posted by Alessandro Abate on 16 Jun 2008.
Groups: chess
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